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   2020| January-March  | Volume 10 | Issue 1  
    Online since February 25, 2020

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Metoclopramide-Induced Extrapyramidal Side Effects are Augmented by Domperidone
Ahmad A Almeman
January-March 2020, 10(1):21-24
Metoclopramide is perhaps one of the most common causes of drug-induced movement disorders. It is indicated in several conditions such as nausea, vomiting, diabetic gastroparesis, small bowel intubation, and gastroesophageal reflux. We report a case of a 15-month-old Saudi boy who was first treated for sudden and persistent nausea and vomiting, accompanied by high-grade fever 39.9°C. The physician started treating him with domperidone (Motilium 1 mg/mL oral suspension) 0.25 mg/kg immediate (stat) dose and, hence, he received a total stat dose of 2.5 mg. He was also prescribed paracetamol suppositories for fever at a dose of 15 mg/kg. Later on, another pediatrician decided to administer a stat dose of metoclopramide at approximately 6 p.m. and he received only a single dose of 1 mg metoclopramide I.V. (Primperan), which stopped the nausea and vomiting instantly. The baby was brought back to the same government hospital at 12 a.m., presenting typical extrapyramidal symptoms (EPS). He was treated successfully with only diazepam.
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Development of Muffin Using Palmyra (Borassus flabellifer) Sprout Flour
Rashi M Khatri, Samreen Siddiqui, G. Nagamaniammai, K.A. Athmaselvi
January-March 2020, 10(1):14-20
Context: “Miracle tree” palm tree (Borassus flabellifer) is a traditional plant with multiple health benefits. Sprouts are rich in dietary fibers which help in boosting digestive functions. They also contain good amount of enzymes which are generally not available through food. Aims: The aim of present work is to highlight the importance of these underutilized palmyrah sprouts by converting them into flour along with its utilization in new product development. This flour was utilized for development of a popular bakery product − muffins. Settings and Design: For the preparation of muffins, palmyrah flour was combined with refined wheat flour in different ratios (30%, 40%, 50% and 60%). Methods and Material: The physico-chemical properties and proximate composition of the flour were calculated by standard methods. The final product was evaluated based on its physical properties like pH, color, texture, and its proximate composition. Statistical Analysis: The obtained values were statistically calculated as Mean ± SD and student’s t-test analysis been carried out to find the level of significance (P < 0.05). Results: The crude fibre content of the palmyrah sprout flour was significantly higher (5.08%) compared to regular whole wheat flour (0.52%). The water activity value of the palmyrah sprout flour was found to be 0.55, which is less compared to wheat flour and hence appropriate to enhance the shelf life of the product. From the sensory results, the muffin with 50% palmyrah sprout flour was found to be most acceptable. Also, the proximate composition of the new palmyrah muffin was found to be favorable compared with refined wheat muffins. Conclusions: The present study included the incorporation of palmyrah sprout flour in muffins at increasing concentrations in order to select the most desirable muffin. The results of sensory and physical analysis of the final selected muffin i.e. the one containing 50% palmyrah sprout flour demonstrated that this flour enhances the nutritional quality of muffins. Thus, the incorporation of palmyrah sprouts flour can be studied for other such value-added products.
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Nutritional Composition of Bovine Colostrum: Palatability Evaluation of Food Products Prepared Using Bovine Colostrum
Nivedita Deepak Dande, Prajakta Jayant Nande
January-March 2020, 10(1):8-13
Introduction: Bovine colostrum is the initial milk secreted by cows during the first day of calving. The aim of this study was to analyze nutritional composition of bovine colostrum and to replace paneer by incorporating bovine colostrum in sweet rice and tikka masala and to evaluate sensory quality and acceptance of recipes. Materials and Methods: For nutritional analysis of bovine colostrum, first day’s bovine colostrum samples of Sahiwal breed were collected in sterile containers. Various nutritional parameters total solids, fat, solid non fat (SNF), protein, moisture, ash, fat soluble vitamins, water soluble vitamins and minerals were studied. Due to its good nutritional composition, steamed bovine colostrum was incorporated in two paneer based recipes, namely sweet rice and tikka masala. Recipes were first standardized & sensory evaluation was conducted by six trained panelists in three trails. Results and Conclusion: Laboratory analysis of bovine samples (per 100 g) showed 15.92% total solids, 2.18 g total fat, 13.74 g solid non fat (SNF), 7.98 g total protein, 84.08% moisture & 0.92 g ash. Fat soluble vitamins & water soluble vitamins such as retinol (0.33 mg), vitamin E (0.29 mg), vitamin D (310.37 mcg), thiamine (0.052 mg), riboflavin (0.384 mg), pyridoxine (0.030 mg), pantothenic acid (0.015 mg) & ascorbic acid (0.016 mg) were estimated in 100 g of bovine colostrum. Niacin, folic acid & biotin were found to be absent in bovine colostrum. The content of calcium, potassium, sulphur, phosphorus & iron was higher in bovine colostrum. Experimental recipes were well accepted for appearance, colour, doneness, texture, flavor & taste with insignificant differences against control recipes at both 5% & 1% (P>0.05). Bovine colostrum was found to be nutritious & surplus bovine colostrum can be incorporated recipes without altering sensory quality.
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Neurotheology—The Triad of Religion, Spirituality, and Neuroscience
Saleem Khaldoon Al-Nuaimi, Musthafa Mohamed Essa, M. Walid Qoronfleh
January-March 2020, 10(1):25-27
Religion and spirituality are fundamental to the human condition and play a role in our mental health and wellbeing. Initially, religion and science thrived in a complimentary relationship, only to be polarized with the aggressive secularization of science. Neurotheology is an exciting new approach that may help bridge our understandings of religion, health and the overall human condition. However, we need to recognize the limitations of this approach and, hence, cautiously interpret any findings.
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Elements of Treatment Adherence in Children with Cow’s Milk Protein Allergy
Fatih Ozdener, Feza Kirbiyik, Anil Akşit, Ali Evrim Doğan, Arzu Baygül, Nermin Güler, CAAAD Study Group
January-March 2020, 10(1):1-7
Background: Adherence with treatment is critical for a successful outcome in cow’s milk protein allergy (CMPA). Determination of the factors associated with non-adherence will enable us to develop effective approaches to increase the adherence rates, thus better cost-effectiveness of the treatment. The aim of this study was to identify the main factors associated with non-adherence with treatment for CMPA in children through the view of the physicians. Materials and methods: This focus-group study involved 51 pediatricians. Data were obtained using face-to-face surveys and subsequent discussions with the physicians. Results: Based on the treating physician’s opinion, adherence to treatment was 65.7%. Of the patients, 55.4% and 29.3% were treated with an amino-acid-based formula (AAF) and an extensively hydrolyzed formula (eHF) with the tolerability rates of 77.4% and 77.2%, respectively. Remaining patients were treated with elimination diet. For patient-related factors, CMPA severity and the existence of underlying morbidities, of family-related factors, the education level of the family and their confidence in the treatment, and of product-related factors, product taste/aroma and formula choice were most strongly associated factors with treatment adherence. Conclusions: The main obstacles in treating CMPA in clinical practice were intolerability or incorrect use of the formula, dislike of its flavor and odor, and difficulties in implementation of elimination diet by parents. Determination of the factors associated with non-adherence is important in order to develop effective strategies to increase the adherence rates which will in turn improve the outcome and cost-effectiveness of the treatment.
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