International Journal of Nutrition, Pharmacology, Neurological Diseases

REVIEW ARTICLE
Year
: 2016  |  Volume : 6  |  Issue : 4  |  Page : 139--145

An empirical review on oxidative stress markers and their relevance in obsessive-compulsive disorder


Sujita Kumar Kar1, Ipsita Choudhury2 
1 Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India
2 Department of Biochemistry, Rama Medical College and Research Institute, Kanpur, Uttar Pradesh, India

Correspondence Address:
Sujita Kumar Kar
Department of Psychiatry, King George«SQ»s Medical University, Lucknow, Uttar Pradesh
India

Oxidative stress results from imbalance in the generation of oxidative free radicals in the body and neutralizing antioxidant mechanisms. It hampers various cellular biochemical processes causing dysfunction of the neurons. Reactive oxygen species and reactive nitrogen species are the two important systems regulating the body«SQ»s oxidative stress. Oxidative stress has a role in several psychiatric disorders including obsessive-compulsive disorder (OCD) and other anxiety disorders. Various studies have found elevated levels of malondialdehyde, superoxide dismutase, glutathione peroxidase, and catalase in patients with OCD, which are considered the markers of oxidative stress. This review discusses the relevance of oxidative stress in OCD.


How to cite this article:
Kar SK, Choudhury I. An empirical review on oxidative stress markers and their relevance in obsessive-compulsive disorder.Int J Nutr Pharmacol Neurol Dis 2016;6:139-145


How to cite this URL:
Kar SK, Choudhury I. An empirical review on oxidative stress markers and their relevance in obsessive-compulsive disorder. Int J Nutr Pharmacol Neurol Dis [serial online] 2016 [cited 2021 Mar 1 ];6:139-145
Available from: https://www.ijnpnd.com/article.asp?issn=2231-0738;year=2016;volume=6;issue=4;spage=139;epage=145;aulast=Kar;type=0