Year : 2016 | Volume
: 6 | Issue : 1 | Page : 1--2
Food, medicine, and disease: A biological tangle for humans
Mohammed Abdul Sattar Khan
Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Massachusetts General Hospital, Shriners Hospital for Children®, Boston, USA
Mohammed Abdul Sattar Khan
Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Massachusetts General Hospital, Shriners Hospital for Children®, Boston
|How to cite this article:|
Khan MA. Food, medicine, and disease: A biological tangle for humans.Int J Nutr Pharmacol Neurol Dis 2016;6:1-2
|How to cite this URL:|
Khan MA. Food, medicine, and disease: A biological tangle for humans. Int J Nutr Pharmacol Neurol Dis [serial online] 2016 [cited 2021 Jul 30 ];6:1-2
Available from: https://www.ijnpnd.com/text.asp?2016/6/1/1/173786
As a member of the International Advisory Board of the International Journal of Nutrition, Pharmacology, Neurological Diseases, I am obliged to ponder and regard the purpose and prospect of this journal in the imminent future.
In the heavens, a man (Adam pbuh) is created with sounding clay, and then a woman (Eve pbuh) from that man. This couple moves freely around in the heavens. Amazingly, they require neither food for survival nor clothes to wear. There is no process of metabolism, no requirement of medicine for them. Most importantly, the possibility of prognosis or diagnosis and treatment of any disease is null. These characteristics make them “Superbeings.” In other words, they are heavenly “Robots,” but they are warned for only one thing, that is, not to eat a fruit from the prohibited tree. Subsequently, an evil comes into the picture and distracts these Superbeings, leading them to commit the act of plucking a fruit from the prohibited tree. Eventually, they eat it. To their utmost surprise, consuming that fruit from the tree suddenly transforms these heavenly “Superbeings” or “Robots” into temporal human beings. Essentially, they are now in dire need of food three times a day to survive, and their metabolic and biochemical processes are activated, leading them to the earth to reproduce and spread.
Now on earth, they are searching for food (nutrition) and have to worry about medicine (pharmacology) and diseases (neurological, etc.). They have been meeting many challenges since their arrival to stay on the survival track. The possibility of metabolic derailment, prognosis and/or diagnosis of disease, has become factual and medicine is needed for its prevention or cure. Evidently, consuming the fruit has trapped human beings in an eternal triangle of nutrition, pharmacology, and diseases.
Nutrition is a key component that can nourish various systems of the body and maintain a long and healthy life. The lack of food, that is, malnutrition, places humans in danger because of metabolic derailment. On the other hand, excessive food consumption also leads to several health issues. Balanced nutrition through an appropriate proportion of antioxidants, carbohydrates, fats, minerals, proteins, vitamins, and water is crucial to provide energy and immunoprotection. The human body needs these components as a fuel source for regular body maintenance—to keep the body weight right, to boost immune system and chiefly to protect from diseases. In other words, “proper nutrition is a key to a healthy life.”
Pharmacology is an excellent scientific tool to determine the effects of biologically active chemical compounds, to dissect molecular mechanisms, and to develop a medicine in order to treat a patient with a particular ailment. Although there has been a huge increase in pharmacological studies of synthetic compounds, the progress in the development of new drugs is still lagging behind. The challenges are manifold, and demands are unmet because of the side effects associated with the drugs, which apparently make them clinically insignificant. Unfortunately, in this situation the urge rises to discover new drugs from natural products or nutraceuticals. In order to fill this vacuum, investigators are turning their attention toward the pharmacology of natural products with optimism that this approach will meet their expectations and pave their way to successful drug discovery.
The mother of all diseases is aging, which has been very well described here: “We have indeed created man in best shape. Then reduced him to lowest of the low states” (Quran, 95:4–5). Although normal aging in any circumstance is inevitable, the occurrence of diseases ahead of time, especially during childhood, is the real matter of concern. New pharmaceutical drugs are taking their place on the shelves of pharmacies around the world to prevent or cure diseases at an early stage, but on the flip side, new diseases are emerging. For example, we have not yet even found a complete cure to a number of known neurological diseases, such as Alzheimer&'s and Parkinson&'s, or to new diseases such as the childhood neurological disease pontocerebellar hypoplasia, which was discovered in 2014 and has contributed to the struggle in drug discovery. It is evident that this journal is only beginning to report the discovery of new drugs and their targets, and to unveil a myriad of molecular mechanisms involved in the neurological diseases.
The International Journal of Nutrition, Pharmacology, Neurological Diseases has become a wonderful resource to communicate new and promising discoveries covering three major scientific areas, namely, nutrition, pharmacology, and neurological diseases. This journal has revived and connected these three disciplines on a single platform to untangle the secrets of human suffering. This journal has also evolved over the past several years by making inroads into Journal Citation Reports, Google Scholar, and Scopus, and indexing in several scientific databases by becoming an internationally known journal within a short period of time. The best part of this journal is that it covers the most important aspects of this type of scientific investigation under one umbrella and gathers outstanding scientists in the field around the world to provide input on the current research in these disciplines.