International Journal of Nutrition, Pharmacology, Neurological Diseases

REVIEW ARTICLE
Year
: 2014  |  Volume : 4  |  Issue : 4  |  Page : 198--202

Future prospective and current status of antioxidants in premalignant and malignant lesions of oral cavity


Shalu Rai, Rohit Malik, Deepankar Misra, Akshay Sharma 
 Department of Oral Medicine and Radiology, Institute of Dental Studies and Technologies, Modinagar, Uttar Pradesh, India

Correspondence Address:
Shalu Rai
C 1 Sector 23, Noida 201 301, Uttar Pradesh
India

In the late 19 th and early 20 th century, extensive study was devoted to the use of antioxidants in important industrial processes, such as the prevention of metal corrosion, vulcanization of rubber, and polymerization of fuels in the fouling of internal combustion engines. In recent years, there is an upsurge in the areas related to newer developments in prevention of disease, especially the role of free radicals and antioxidants. So it will be pertinent to examine the possible role of «SQ»free radicals«SQ» in disease and «SQ»antioxidants«SQ» in its prevention. Antioxidants are intimately involved in the prevention of cellular damage-the common pathway for cancer and a variety of diseases. The reversal or suppression of premalignant lesions is an important strategy against carcinogenesis for the prevention of cancer. Whether antioxidants can protect the human population from diseases like leukoplakia, lichen planus, carcinoma in situ or oral cancer and also from cancers of the upper aero digestive tract i.e. larynx, pharynx and esophagus and increase the life expectancy is still controversial. This article deals with the action of various chemopreventive agents along with brief review of literature about the outcome of effect of antioxidant on potentially premalignant and malignant lesions of oral mucosa.


How to cite this article:
Rai S, Malik R, Misra D, Sharma A. Future prospective and current status of antioxidants in premalignant and malignant lesions of oral cavity.Int J Nutr Pharmacol Neurol Dis 2014;4:198-202


How to cite this URL:
Rai S, Malik R, Misra D, Sharma A. Future prospective and current status of antioxidants in premalignant and malignant lesions of oral cavity. Int J Nutr Pharmacol Neurol Dis [serial online] 2014 [cited 2020 Nov 24 ];4:198-202
Available from: https://www.ijnpnd.com/article.asp?issn=2231-0738;year=2014;volume=4;issue=4;spage=198;epage=202;aulast=Rai;type=0