International Journal of Nutrition, Pharmacology, Neurological Diseases

ORIGINAL ARTICLE
Year
: 2012  |  Volume : 2  |  Issue : 2  |  Page : 132--134

Effects of the petroleum ether extract of Amorphophallus paeoniifolius on experimentally induced convulsion in mice


Shankhajit De1, Yadu Nandan Dey2, Sudesh Gaidhani2, Sarada Ota2 
1 Department of Pharmacology, Vinayaka Missons Sikkim College of Pharmaceutical Sciences, Vinayaka Missons Sikkim University, NH 31-A, Tadong, East Sikkim, India
2 Pharmacology section, Central Council for Research in Ayurveda and Siddha, Department of AYUSH, Ministry of Health and F.W., Govt. of India, Opp. 'D' Block, Janakpuri, New Delhi, India

Correspondence Address:
Yadu Nandan Dey
Central Council for Research in Ayurveda and Siddha, Department of AYUSH, Ministry of Health and F.W., Govt. of India, Opp. SQDSQ Block, Janakpuri, New Delhi 58
India

Aim: To study the anticonvulsant activity of Amorphophallus paeoniifolius. Materials and Methods: Petroleum ether extracts of Amorphophallus paeoniifolius at the dose of 200, 300, 400 mg/kg were used for the effects on the onset of convulsion in Isoniazid (INH) induced mice model. Diazepam at the dose of 4 mg/kg was used as the standard drug. Result: Petroleum ether extracts of Amorphophallus paeoniifolius showed dose-dependent activity regarding onset of convulsion. Conclusion: Hence from the above study it has been concluded that Amorphophallus paeoniifolius has anticonvulsant activity.


How to cite this article:
De S, Dey YN, Gaidhani S, Ota S. Effects of the petroleum ether extract of Amorphophallus paeoniifolius on experimentally induced convulsion in mice.Int J Nutr Pharmacol Neurol Dis 2012;2:132-134


How to cite this URL:
De S, Dey YN, Gaidhani S, Ota S. Effects of the petroleum ether extract of Amorphophallus paeoniifolius on experimentally induced convulsion in mice. Int J Nutr Pharmacol Neurol Dis [serial online] 2012 [cited 2021 Jan 21 ];2:132-134
Available from: https://www.ijnpnd.com/article.asp?issn=2231-0738;year=2012;volume=2;issue=2;spage=132;epage=134;aulast=De;type=0