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REVIEW ARTICLE
Year : 2021  |  Volume : 11  |  Issue : 1  |  Page : 17-26

Sleep and Gonadotrophin Hormones


1 Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, India
2 Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru,Centre for Experimental Pharmacology and Toxicology, Central Animal Facility, JSS Academy of Higher Education & Research, Mysuru, India
3 Department of Physiology, Saveetha Medical College & Hospital, Thandalam, Chennai, India
4 Department of Traditional Food & Sensory Science, CSIR − Central Food Technological Research Institute (CFTRI), Mysuru, India
5 Centre for Biodiversity Research, Dhofar University, Salalah, Oman
6 Department of Food Science and Nutrition, CAMS, Sultan Qaboos University, Muscat, Oman
7 Department of Biochemistry, Panimalar Medical College Hospital and Research Institute, Chennai, India
8 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India
9 Department of Biomedical Sciences, School of Medicine, Nazarbayev University, Nur-Sultan City, Kazakhstan
10 Research and Policy Department, World Innovation Summit for Health (WISH), Foundation, Doha, Qatar

Correspondence Address:
MBA M. Walid Qoronfleh
Research and Policy Department, World Innovation Summit for Health (WISH), Qatar Foundation, P.O. Box 5825, Doha
Qatar
PhD, MBA Saravana Babu Chidambaram
Research and Policy Department, World Innovation Summit for Health (WISH), Qatar Foundation, P.O. Box 5825, Doha
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnpnd.ijnpnd_97_20

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Sleep plays a key role in neuroendocrine functioning and glucose metabolism. Currently existing data reveal that restriction of sleep duration results in adverse health effects. Sleep plays an imperative role in endocrine systems. Sleep causes the episodic secretion of gonadotrophin through modulation of neurotransmitters activity. Research on the significance of sex and gonadotrophic hormone in causing sleep disparities and its effects on cognition among men and women is gaining increased awareness. Epidemiologic, preclinical, and clinical studies have reported that sleep deprivation causes alteration of metabolic endocrine functions, including reduced glucose tolerance, insulin sensitivity, and leptin levels with increased cortisol and ghrelin levels. Men with lesser levels of testosterone and women with elevated levels of progesterone are more susceptible to the effects of sleep restriction on cognition and emotion processing tasks. The present integrative review highlights the effects of sleep deprivation on sex and gonadotrophin hormones and its link to cognitive function.


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