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Year : 2017  |  Volume : 7  |  Issue : 3  |  Page : 45-53

Memory Impairment With Reference to Alzheimer’s Disease: An Update

Department of Pharmacology, School of Pharmacy, Babu Banarasi Das University, Lucknow, Uttar Pradesh, India

Correspondence Address:
Mayank Kulshreshtha
Department of Pharmacology, School of Pharmacy, Babu Banarasi Das University, Lucknow, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijnpnd.ijnpnd_7_17

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Dementia or memory loss is the hallmark symptom of Alzheimer’s disease (AD). The exploration of AD helps to identify the problems involved in neural structures such as the default network and role of genetic factors. Episodic memory (EM) directly deals with the memory system that allows an individual to consciously retrieve an old experience or an episode of life. EM plays an important role in AD. The World Health Organization predicts that, by 2025, about 75% of the estimated 1.2 billion people aged 60 years and older will reside in developing countries. It is estimated that the number of people living with dementia will almost double every 20 years to 42.3 million in 2020 and 81.1 million in 2040. In India, there are lesser number of good quality scientific studies/researches that deal with the real trend of the disease and determine the mechanism involved, risk factors, investigations on dementia, decline in awareness, and inadequate availability of social benefit. India is a country with varied cultures, and, therefore, conducting a genetic epidemiological study here has greater advantage. The goal of this review is to provide knowledge and increase the awareness of dementia associated with AD, as well as to understand the mechanism involved and its treatment, which can be useful for researchers or scientists in the near future.

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