| REVIEW ARTICLE |
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| Year : 2015 | Volume
: 5
| Issue : 1 | Page : 1-5 |
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Alcohol, glycine, and gastritis
Shubham Singh, Supraj Raja Sangam, Venkateshwara Rao Joginapally, Senthilkumar Rajagopal
Department of Zoology, Nizam College, Hyderabad, Telangana, India
Correspondence Address:
Senthilkumar Rajagopal
Department of Zoology, Nizam College, Hyderabad, Telangana
India
 Source of Support: This work was supported by Department of
Biotechnology, Ministry of Science and Technology, Govt. of India to
R.S (BT/RLF/Re-entry/42/2012)., Conflict of Interest: None  | Check |
DOI: 10.4103/2231-0738.150065
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Alcohol, or ethanol, is an aggressive factor for the gastrointestinal tract (GI). Alcohol may regulate the function and structure of gastrointestinal segments. In the stomach, alcohol modulates the gastric acid secretion and the activity of muscles surrounding the stomach. The inflammation in the lining of the stomach is termed gastritis. It may be due to excessive alcohol consumption, long-term use of the nonsteroidal anti-inflammatory drugs (NSAIDS), and other factors. Glycine is the smallest of the 20 amino acids commonly found in proteins, and indeed is the smallest possible. Moreover, elevation of blood glycine has shown a remarkable improvement in shock, alcoholic liver injury, gastric inflammation, some forms of cancer, nephrotoxicity, and it can also act as an anti-inflammatory immunonutrient. This article will discuss the responsible mechanisms of protection against gastric and hepatic toxicity, and review the beneficial effects of glycine in alcohol-induced inflammation. |
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