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A comprehensive review on herbal drugs for hepatoprotection of 21 st Century
Rakesh Sagar1, Amrita Bhaiji1, Fedelic Ashish Toppo2, Bandana Rath3, Himanshu Bhusan Sahoo4
1 Department of Pharmacognosy and Phytochemistry, Sri Satya Sai Institute of Pharmaceutical Science, Bhopal, Madhya Pradesh, India
2 Pharmacognosy and Phytochemistry Laboratory, Faculty of Pharmacy, Vidya Niketan Samiti Group of Institutions, Bhopal, Madhya Pradesh, India
3 Department of Pharmacology, Maharaja Krishna Chandra Gajapati Medical College and Hospital, Berhampur, Odisha, India
4 Department of Pharmacology and Toxicology, Vedica College of B. Pharmacy, Bhopal, Madhya Pradesh, India
Correspondence Address:
Himanshu Bhusan Sahoo
Department of Pharmacology and Toxicology, Vedica College of B. Pharmacy, Bhopal, 462033, Madhya Pradesh
India
 Source of Support: Ayushmati Educational Society, Bhopal,
Madhya Pradesh, India., Conflict of Interest: None  | Check |
DOI: 10.4103/2231-0738.139397
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Liver is a vital organ that plays a major role in metabolism and excretion of xenobiotics from the body. Liver injury or liver dysfunction is a major health problem that challenges not only health care professionals but also the pharmaceutical industry and drug regulatory agencies. Liver cell injury caused by various toxic chemicals (certain anti-biotics, chemotherapeutic agents, carbon tetrachloride (CCl 4 ), thioacetamide (TAA) etc.), excessive alcohol consumption and microbes is well-studied. The available synthetic drugs to treat liver disorders in this condition also cause further damage to the liver. Hence, herbal drugs have become increasingly popular and their use is wide spread. Herbal medicines have been used in the treatment of liver diseases for a long time. A number of herbal preparations are available in the market. The present review is aimed at compiling data on promising phytochemicals from medicinal plants that have been tested in hepatotoxicity models using modern scientific system. |
