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Year : 2013  |  Volume : 3  |  Issue : 2  |  Page : 142-145

Wernicke's encephalopathy and Hyperemesis gravidarum

1 Department of Obstetrics and Gynecology/ Northern Area Hospital, Hamad Medical Corporation; Doha, Qatar
2 Department of Internal Medicine/NAH, Hamad Medical Corporation; Doha, Qatar

Correspondence Address:
Ummunissa Firdous
Department of OBGY/NAH, Hamad Medical Corporation, Doha
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2231-0738.112841

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Recent research is concentrated around micronutrients and antioxidant's role in degenerative neurological disorders; but still the vitamin deficiency in special situations can lead to life threatening medical emergencies. Hyperemesis gravidarum rarely leads to Wernicke's encephalopathy. It is a medical metabolic neurological emergency. Wernicke's encephalopathy is manifested by triad of confusion, opthalmoplegia and ataxia. Early detection and proper supplementation of thiamine is essential for treatment. Clinical manifestations of Wernicke's encephalopathy are due to the involvement of specific area of the brain where thiamine content and turnover is maximized. We report a case of Wernicke's encephalopathy in a pregnant woman known to have thyroid disorder, hyperemesis gravidarum; she was managed with intravenous dextrose infusion. The condition was diagnosed early by clinical manifestations and improved dramatically with thiamine supplementation. Wernicke's encephalopathy occurring due to hyperemesis gravidarum and hyperthyroidism is rare. High index of suspicion is essential for early diagnosis and proper supplementation of thiamine.

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