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Year : 2012  |  Volume : 2  |  Issue : 2  |  Page : 100-104

Anti-edematogenic and analgesic activities of Ficus benghalensis

Department of Pharmacology, S. S. D. J. College of Pharmacy, Neminagar, Chandwad, Maharashtra, India

Correspondence Address:
Manoj S Mahajan
Department of Pharmacology, SNJB'S SSDJ College of Pharmacy, Neminagar, Chandwad, Dist. Nashik 423 101
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2231-0738.95936

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This work was done for the investigations of anti-inflammatory and analgesic activities of methanolic extract of dried leaves of Ficus benghalensis Linn. by oral administration at doses of 10, 20 and 100 mg/kg of body weight to healthy animals. The extract was studied for anti-inflammatory activity by using carrageenan-induced hind paw edema in rats. The mean increases in paw volume and % inhibition in the edema were measured plethysmometrically at different time intervals after carrageenan (1% w/v) injection. The extract was also evaluated for analgesic activity using acetic acid-induced writhing and Eddy's hot plate method in albino mice. The methanolic extract of F. benghalensis showed significant (P<0.05) reduction in carrageenan-induced paw edema and analgesic activity evidenced from decreased acetic acid-induced writhings and increased reaction time in Eddy's hot plate method. Results of present studies suggest that methanolic extract of F. benghalensis possesses significant (P<0.05) anti-inflammatory and analgesic activities.

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