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  Indian J Med Microbiol
 

Figure 2 Photomicrographs of a longitudinal sections at the knee joint of different groups. (A and B) Section of the knee joint of the control group showing intact smooth articular surface (arrows) overlying the subchondral plate of bone (P). Deeper, chondrocytes are located inside their lacunae forming cell nests (N). (H&E; ×100). (C) Section at the knee joint of the arthritic group showing distortion of the articular cartilage and loss of the rounded contour (arrows). Chondrocytes in the superficial zone (S) are distorted. (H&E; ×100). (D) Section at the knee joint of the OMEGA-treated group showing restoration of the smooth articular surface (arrows), aggregation of chondrocytes with the formation of cell nests (N). A blood vessel can be observed (*) (H&E; ×400). (E) Section at the knee joint of the DEX-treated group showing restoration of the smooth articular surface (arrows). Proliferation of chondrocytes can be observed (arrowhead) (H&E; ×400). (F) Section at the knee joint of the MTX-treated group showing restoration of the smooth articular surface (arrows) (H&E; ×100). (G) Section at the knee joint of the OMEGA combined with DEX-treated group showing restoration of the smooth rounded articular surface (arrows). The subchondral plate of bone can be observed (P) (H&E; ×100). (H) Section at the knee joint of the OMEGA combined with MTX-treated group showing restoration of the smooth articular surface (arrows). Hypercellularity and colonization of chondrocytes can be observed (arrowhead). (H&E; ×100). DEX, dexamethasone; H&E, hematoxylin and eosin; MTX, methotrexate; OMEGA, omega-3.

Figure 2 Photomicrographs of a longitudinal sections at the knee joint of different groups. (A and B) Section of the knee joint of the control group showing intact smooth articular surface (arrows) overlying the subchondral plate of bone (P). Deeper, chondrocytes are located inside their lacunae forming cell nests (N). (H&E; ×100). (C) Section at the knee joint of the arthritic group showing distortion of the articular cartilage and loss of the rounded contour (arrows). Chondrocytes in the superficial zone (S) are distorted. (H&E; ×100). (D) Section at the knee joint of the OMEGA-treated group showing restoration of the smooth articular surface (arrows), aggregation of chondrocytes with the formation of cell nests (N). A blood vessel can be observed (*) (H&E; ×400). (E) Section at the knee joint of the DEX-treated group showing restoration of the smooth articular surface (arrows). Proliferation of chondrocytes can be observed (arrowhead) (H&E; ×400). (F) Section at the knee joint of the MTX-treated group showing restoration of the smooth articular surface (arrows) (H&E; ×100). (G) Section at the knee joint of the OMEGA combined with DEX-treated group showing restoration of the smooth rounded articular surface (arrows). The subchondral plate of bone can be observed (P) (H&E; ×100). (H) Section at the knee joint of the OMEGA combined with MTX-treated group showing restoration of the smooth articular surface (arrows). Hypercellularity and colonization of chondrocytes can be observed (arrowhead). (H&E; ×100). DEX, dexamethasone; H&E, hematoxylin and eosin; MTX, methotrexate; OMEGA, omega-3.