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  Indian J Med Microbiol
 

Figure 11: (a-e) Photomicrographs of heart tissue of normal and ISO treated rats (H and E, ×20). (a) Normal histological appearance of myocardium. (b) ISO-treated positive control shows confluent myocardial necrosis, fragmentation and infiltration with macrophages. (c) Carvedilol treated group (2 mg/kg) shows mild interstitial edema and focal degeneration of myofibres. (d) Heartogen (50 mg/kg)-treated group shows focal myocardial necrosis and fragmentation, interstitial edema, macrophage infiltration. (e) Heartogen (100 mg/kg)-treated group shows mild interstitial edema and focal excess contraction of myofibres

Figure 11: (a-e) Photomicrographs of heart tissue of normal and ISO treated rats (H and E, ×20). (a) Normal histological appearance of myocardium. (b) ISO-treated positive control shows confluent myocardial necrosis, fragmentation and infiltration with macrophages. (c) Carvedilol treated group (2 mg/kg) shows mild interstitial edema and focal degeneration of myofibres. (d) Heartogen (50 mg/kg)-treated group shows focal myocardial necrosis and fragmentation, interstitial edema, macrophage infiltration. (e) Heartogen (100 mg/kg)-treated group shows mild interstitial edema and focal excess contraction of myofibres