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CASE REPORT
Year : 2015  |  Volume : 5  |  Issue : 3  |  Page : 110-112

Can the combination of lithium and olanzapine be an effective treatment strategy in the management of bipolar disorder with Wilson's disease?


1 Department of Psychiatry, Institute of Human Behavior and Allied Sciences, Delhi, India
2 Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India
3 Department of Community Medicine, Subharti Medical College, Meerut, Uttar Pradesh, India

Correspondence Address:
Dr. Sujita Kumar Kar
Department of Psychiatry, King George's Medical University, Lucknow - 226 003, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-0738.158376

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Wilson's disease is a disorder of copper metabolism, which frequently has neurobehavioral manifestations due to the involvement of the central nervous system (CNS). Depression is the commonest neuropsychiatric manifestation; however, recent studies have revealed the association of bipolar disorder with Wilson's disease. Lithium is a safe and efficacious medication in the management of bipolar disorder in Wilson's disease. Our case report highlights the efficacy of the combination of lithium and olanzapine in the management of bipolar disorder in the context of Wilson's disease.


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