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CASE REPORT
Year : 2015  |  Volume : 5  |  Issue : 3  |  Page : 108-109

Autoimmune encephalitis masquerading as psychosis: Diagnostic and therapeutic challenge


1 Department of Psychiatry, Institute of Human Behaviour and Allied Sciences (IHBAS), Delhi, India
2 Department of Neurology, Institute of Human Behaviour and Allied Sciences (IHBAS), Delhi, India

Correspondence Address:
Dr. Prerna Kukreti
Department of Psychiatry, Institute of Human Behaviour and Allied Sciences (IHBAS), Delhi - 110 095
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-0738.158373

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Autoimmune encephalitis often presents as neuropsychiatric syndromes and may be mistaken for a primary psychiatric disorder. We report a case of a young woman with a history of acute psychosis and focal seizure, with normal neuroimaging, electroencephalogram, and cerebrospinal fluid (CSF) study. Serum tested positive for the N-methyl-D-aspartate receptor (NMDAR) antibody, and the patient improved upon starting steroids. There is a need to screen for autoimmune causes in case of neuropsychiatric syndromes presenting with seizure or dyskinesias and alteration of sensorium. Prompt diagnosis and appropriate management can be life-saving.


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