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Year : 2014  |  Volume : 4  |  Issue : 1  |  Page : 4-10

Carcinogens and cancer preventors in diet


1 Department of Oral Medicine, Diagnosis and Radiology, CSMSS Dental College and Hospital, Aurangabad, Maharashtra, India
2 Department of Conservative Dentistry and Endodontics, MGM Dental College and Hospital, Navi Mumbai, Maharashtra, India

Correspondence Address:
Neha Khambete
C/o, khambete hospital, ward no. 1, opp. Railway goods yard, shrirampur - 413 709, maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-0738.124609

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Cancer is a major burden on the health-care system world-wide not only in the developed countries, but also in the developing countries. Several lines of evidence indicate that diet and nutrition can contribute to human cancer risk. Diet is an important factor in determining cancer incidence in many countries and regions. Diet components relevant to cancer development can be divided into macro-and micro-components. Diet can have both positive and negative effects on carcinogenesis. Several substances in diet such as heterocyclic amines, polycyclic aromatic hydrocarbons, N-nitroso compounds and alcohols have been associated with increased risk of cancer, whereas certain compounds such as phytochemicals and probiotics have cancer preventing properties. This paper aims to review the carcinogenic and cancer preventive properties of dietary substances and their possible mechanisms of action.


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