Users Online: 1264

Home Print this page Email this page Small font sizeDefault font sizeIncrease font size

Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts | Login 
     
ORIGINAL ARTICLE
Year : 2013  |  Volume : 3  |  Issue : 3  |  Page : 263-268

Susceptibility of Cronobacter sakazakii to plant products, antibiotics, and to lactic acid bacteria


Department of Zoology, Environmental Biotechnology Laboratory, Dayalbagh Educational Institute, Dayalbagh Agra, Uttar Pradesh, India

Correspondence Address:
Alka Prakash
Department of Zoology, Environmental Biotechnology Laboratory, Dayalbagh Educational Institute, Dayalbagh Agra - 282 110, Uttar Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-0738.114847

Rights and Permissions

Introduction: Cronobacter sakazakii is an emerging and opportunistic pathogen, related with outbreaks of necrotizing enterocolitis, bacteremia, and infant meningitis. Powdered infant formula (PIF)-products contaminated by C. sakazakii cause severe infections in infants. Materials and Methods: In the present study, C. sakazakii isolates were tested for their susceptibility to various antibiotics using the Kirby-Bauer disk diffusion method. Alternatively, C. sakazakii infections can be controlled by various plant products and probiotics. Aqueous and alcoholic extracts of Citrus sinensis, Cinnamomum zeylanicum, Piper chaba, Terminalia chebula, Terminalia arjuna, Mangifera indica, Zingiber officinale, Allium sativum, Azadirachta indica, Ocimum sanctum, Syzygium aromaticum, Terminalia bellirica and Emblica officinalis were prepared and their antimicrobial activities were checked against C. sakazakii by the Muller-Hinton Agar well diffusion method. For probiotic control, an in vitro study was conducted to determine the antibacterial activity of lactic acid bacteria against C. sakazakii. Results: Results showed the antimicrobial activity of plant products and lactic acid bacteria against C. sakazakii. It is recommended that these plant products and lactic acid bacteria could be utilized as natural antimicrobials in baby food-formulations to inhibit C. sakazakii infections in neonates. Conclusion: Emergence of multi-drug resistance and side-effects of antibiotics, plant products can serve as effective antimicrobial agents against C. sakazakii. Lactic acid bacteria can also serve in the control of infections caused by C. sakazakii. Specific probiotics may be useful for healthy intestinal colonization and barrier function to fight pathogen adhesion.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3230    
    Printed69    
    Emailed1    
    PDF Downloaded200    
    Comments [Add]    
    Cited by others 1    

Recommend this journal