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REVIEW ARTICLE
Year : 2013  |  Volume : 3  |  Issue : 3  |  Page : 229-235

Photochemotherapy: A review


1 Department of Oral Medicine and Radiology, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India
2 Department of Oral and Maxillofacial Surgery, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India
3 Department of Oral Medicine and Radiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Pattammal Elumalai Chandra Mouli
Department of Oral Medicine and Radiology, Sri Venkateswara Dental College and Hospital, OMR Road, Off Navalur, Thalambur, Chennai 603 103, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-0738.114840

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Photochemotherapy (PUVA) is a type of ultraviolet radiation (UVA). Treatment (phototherapy) used for severe skin diseases. PUVA is a combination treatment, which consists of Psoralens (P) and then exposing the skin to long wave UVA. PUVA has become a useful alternative in dermatologic therapy. Starting from historical date up to modern era the safe and useful modes of PUVA has been documented in many immunological disorders. PUVA is useful for patients with various skin disorders, including psoriasis, dermatitis, polymorphic light eruption, and mycosis fungoides. The number and the frequency of PUVA treatments will depend on the condition being treated and individual factors. Despite side effects and potential long-term hazards, PUVA is shown in clinical routine as an effective alternative to conventional immunosuppressive therapy. A wide range of diverse field for its possible utility provides an alternative armamentarium in many immunological disorders for dermatologist and also for oral diagnostician.


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