Users Online: 752

Home Print this page Email this page Small font sizeDefault font sizeIncrease font size

Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts | Login 
     
CASE REPORT
Year : 2013  |  Volume : 3  |  Issue : 2  |  Page : 146-149

Pemphigus vulgaris of oral cavity: A case report with its treatment strategies


1 Department of Oral and Maxillofacial Pathology, ITS-CDSR (Muradnagar), Ghaziabad, Uttar Pradesh, India
2 Department of Pharmacology, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India

Correspondence Address:
Seema Kapoor
Department of Oral and Maxillofacial Pathology, ITS-CDSR (Muradnagar), Ghaziabad, Uttar Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-0738.112842

Rights and Permissions

Pemphigus vulgaris (PV), a rare autoimmune mucocutaneous blistering disorder, has been reported with incidence of 0.1-0.5 cases per 100,000 individuals worldwide per year. It is slightly more common in women and occurs primarily in adults during the 5 th or 6 th decade of life. The etiology of PV is uncertain but is supposed to be mediated by circulating immunoglobulin G (IgG) autoantibodies against the desmosomal cadherins, desmoglein 1 and 3. Biopsy, light microscopic examination, and additional adjuvant tests, such as immunofluorescence studies can be used to establish the diagnosis. In most cases (70-90%), the first signs of disease appear on the oral mucosa but most patients with oral lesions are initially misdiagnosed and treated improperly for months or years. If these patients are misdiagnosed or left untreated, PV may be fatal with a mortality rate ranging from 60% to 90%. Therefore, here we are trying to discuss basics of diagnosing and treating PV with oral lesions with the help of a case report.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed4974    
    Printed82    
    Emailed0    
    PDF Downloaded377    
    Comments [Add]    

Recommend this journal