Users Online: 233

Home Print this page Email this page Small font sizeDefault font sizeIncrease font size

Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts | Login 
     
ORIGINAL ARTICLE
Year : 2011  |  Volume : 1  |  Issue : 2  |  Page : 179-183

A pathomorphological study of the sublethal toxicity of cypermethrin in Sprague Dawley rats


1 Department of Animal and Veterinary Sciences, College of Agricultural and Marine Sciences, Sultan Qaboos University, Sultanate of Oman;Center of Excellence in Pathology, College of Veterinary and Animal Sciences, Thrissur, Kerala,India
2 Center of Excellence in Pathology, College of Veterinary and Animal Sciences, Thrissur, Kerala,India
3 Center of Excellence in Pathology and Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Thrissur, Kerala, India

Correspondence Address:
Remya R Nair
Department of Animal and Veterinary Sciences, College of Agricultural and Marine Sciences, PO.Box 34, PC. 123, Sultan Qaboos University, Sultanate of Oman

Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-0738.84211

Rights and Permissions

Introduction : A study was undertaken to investigate the potential toxic effects of cypermethrin in adult Sprague Dawley male rats, with particular emphasis on its effect on the nervous and digestive systems. Materials and Methods: The clinical signs, gross and histological alterations were analyzed, to study the effects of different doses of cypermethrin. Results: Medium and high doses produced nervous signs in animals. Gross lesions were observed in the intoxicated groups, such as, bloat, congestion of lungs, heart, brain, pulmonary haemorrhage, and degenerative changes in the liver and kidneys. Microscopically effects on all organs were mild-to moderate degenerative changes at the low-dose level. Medium- and high-dose intoxicated groups revealed necrotic changes, extensive haemorrhages, congestion in organs like liver, kidney, and lungs apart from the changes observed in low-dose group animals. Conclusions: The text to abstract): The present study reveals that cypermenthrin can produce toxic effects in mammals at sublethal doses.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed6971    
    Printed196    
    Emailed0    
    PDF Downloaded313    
    Comments [Add]    
    Cited by others 4    

Recommend this journal